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Prolia discontinuation

Osteoporosis & Bone Health | Last Active: Dec 19, 2025 | Replies (206)

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@awesomemomx2
Do you have to go on to other meds if you get off Prolia shots? I just wanted to get off of them since I've been having bad pain in both legs and my right hip since April of this year. Started on Lyrica a couple of months ago as Tylenol or other pain meds didn't help. Can't hardly stand on my legs when I get up in the morning. I contribute that to the Prolia shots, even though my daughter doesn't agree with me. I read the side effects and that's what I think! Please let me know about taking other meds after you get off of the Prolia. Thanks
Joan

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Replies to "@awesomemomx2 Do you have to go on to other meds if you get off Prolia shots?..."

@jcking1938
Hi, My husband and I saw our doc yesterday and said George wanted to stop Prolia after one injection. The doc was not happy insisting he needed it for Osteoporosis. But she said the rebound would not be a problem until after 2 shots. She strongly suggested he at least take a bisphosphonate pill weekly. They are less likely to cause ONJ. But George said no because of esophical issues including a hiatal hernia. She dismissed this concern. However reputable studies through Pubmed and NIH say pills not recommended for those with hiatal hernias. Very serious side effects. George is 80 and values the quality of life he enjoys. Despite our doctor’s disapproval, he will stop medications. Whatever decision we all make, there are pros and cons. We need to listen to our doctors, weigh our options, check reputable sites, talk to our dentists
( There we heard a very different story about the “rare” side effects of ONJ.), and then do what we feel most comfortable with. We also need to consider our age and how we want our golden years to be.