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Non focal EPE

Prostate Cancer | Last Active: 17 hours ago | Replies (5)

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Profile picture for michaelcharles @michaelcharles

My layman understanding is that EPE is a negative finding that statistically could increase the risk of recurrence.
My post-op pathology confirmed G 9 (never had a Decipher) with clear margins, lymph nodes and seminal vesicles. Also identified EPE.
My 90 day post-op PSA was .19, not undetectable and labeled "persistent PSA". Repeat PSA 30 days later confirmed .18
Led me to Salvage Radiation Treatment with short term ADT.
That's the "bad news" of my story.
The good news is that I have been undetectable < .02 uPSA for 2 years following Salvage Treatment.
My understanding is that BCR rates post RP are in the 25 - 35% range. I have not seen any direct prediction of recurrence based solely on EPE, but there may be info available.
As with all of us, only time will tell. Hopefully your other Path report results will portend an extended PCa free time period for you
Best wishes.

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Replies to "My layman understanding is that EPE is a negative finding that statistically could increase the risk..."

@michaelcharles
EPE is independent prognostic factor for BCR. It does increase likelihood of it happening at some point. But not all patients with EPE have BCR .