@cookercooker it is appalling that your questions were not answered. In a clinical trial these markers may be used in the data analysis to see if they are useful for monitoring cases like yours. In real clinical use, these markers *may* indicate other cancers in different organ systems, but they would only be raising a flag that would require follow-up, they are not diagnostic in and of themselves. For example, people with high ca 19-9 sometimes have pancreatic cancer or bile duct cancer, but they can also have an inflammation of the pancreas or even gall bladder issues. Do you have a new oncologist besides the clinical trial team, or do they have an oncologist who will answer your questions about the possible need for follow-up?