@1995victoria

Based on this, there's no reason to think that your (or anyone else's) endometrial cancer has anything to do with your JAK2 mutated ET.

The V617F mutation occurred in one of the stem cells that makes blood cells. It's an activating mutation.

JAK2 inactivating mutations occur rarely in endometrial cancers, which are derived from cells of the lining of the uterus. They are completely different mutations, and it's very unlikely that your endometrial cancer even has one.