@packman7
Even with ultrasound guided biopsy, they only get about one percent of the prostate. If an MRI showed Pirads 3-5 And they got those specific spots then it definitely increases the chance of Having relevant information. You just find so many people that have a biopsy and find they are 3+4 or 4+3 after a prostatectomy find it’s much higher. Not all the spots in the prostate appear to be showing a PIRADS visible Tumor.

I still consider that kind of biopsy much better and gives you a really good chance of getting accurate information.