Just joined, biopsy shows 4+4 (Group 4)

Posted by billnumber6 @billnumber6, 1 day ago

My rising PSA, 5 years after Proton treatment prompted a PSMA/PET scan, followed by biopsy at Johns Hopkins. Biopsy shows 4+4 (Group 4) cancer, Can find no info on biopsy accuracy of previously radiated prostate tissue, but assume I will need treatment anyway. Are focal treatments possible or is it prostatectomy/ADT only? I would be grateful for any shared experiences of those in a similar situation.

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Profile picture for billnumber6 @billnumber6

@jeffmarc
Not news, but news to me, I just found out Dr. Epstein is no longer at Johns Hopkins, having been put on administrative leave amid misconduct allegations.
(Feb. 2024)

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@billnumber6 He later resigned. The allegations (not proven in court) sound nasty:

❝Epstein, according to the report, was accused by other doctors of pressuring them to change diagnoses and defer to his wishes over several years. In some cases, according to the people familiar with the accusations, doctors said they felt pressured to give second opinions that agreed with diagnoses made by Epstein’s wife, a pathologist at a urology center in Beltsville, Md. In one case, a misdiagnosis led to a patient’s bladder being removed, according to the report and the people.❞

Source: https://centerforhealthjournalism.org/our-work/reporting/prominent-pathologist-leaves-johns-hopkins-after-allegations

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Profile picture for northoftheborder @northoftheborder

@billnumber6 He later resigned. The allegations (not proven in court) sound nasty:

❝Epstein, according to the report, was accused by other doctors of pressuring them to change diagnoses and defer to his wishes over several years. In some cases, according to the people familiar with the accusations, doctors said they felt pressured to give second opinions that agreed with diagnoses made by Epstein’s wife, a pathologist at a urology center in Beltsville, Md. In one case, a misdiagnosis led to a patient’s bladder being removed, according to the report and the people.❞

Source: https://centerforhealthjournalism.org/our-work/reporting/prominent-pathologist-leaves-johns-hopkins-after-allegations

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@northoftheborder
sounds serious! and to think people have been trusting his opinions for decades....

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Profile picture for northoftheborder @northoftheborder

@billnumber6 He later resigned. The allegations (not proven in court) sound nasty:

❝Epstein, according to the report, was accused by other doctors of pressuring them to change diagnoses and defer to his wishes over several years. In some cases, according to the people familiar with the accusations, doctors said they felt pressured to give second opinions that agreed with diagnoses made by Epstein’s wife, a pathologist at a urology center in Beltsville, Md. In one case, a misdiagnosis led to a patient’s bladder being removed, according to the report and the people.❞

Source: https://centerforhealthjournalism.org/our-work/reporting/prominent-pathologist-leaves-johns-hopkins-after-allegations

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@northoftheborder

This does sound troubling on the surface, but later in the document you give the link to, it said this

The hospital’s review, Epstein said, included the case involving the bladder. He said that an outside pathologist “agreed with my diagnosis and concluded that other pathologists would have arrived at the same diagnosis given the limited nature of the specimen, its morphology, and what clinical information I had at the time of the biopsy.”

The review, Epstein said, “concluded that all of these diagnoses were within good practice and what a reasonable pathologist would have diagnosed in the same situation.”

This seems to make the bladder report less damaging.

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Profile picture for jeff Marchi @jeffmarc

@northoftheborder

This does sound troubling on the surface, but later in the document you give the link to, it said this

The hospital’s review, Epstein said, included the case involving the bladder. He said that an outside pathologist “agreed with my diagnosis and concluded that other pathologists would have arrived at the same diagnosis given the limited nature of the specimen, its morphology, and what clinical information I had at the time of the biopsy.”

The review, Epstein said, “concluded that all of these diagnoses were within good practice and what a reasonable pathologist would have diagnosed in the same situation.”

This seems to make the bladder report less damaging.

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@jeffmarc They're quoting his self-justification for balance. It's also untested in any court or review, since he left before they could assess the allegations.

Unfortunately, that leaves us having to decide between Dr Epstein and his many professional accusers without a full and transparent review of the evidence.

If the allegations are true (and we have no way now of knowing), it would hardly be the first time that a brilliant and talented person let their ego and confidence outstrip their ability.

You've heard the old joke, perhaps?

Q: What's the difference between surgeon and God?

A: God knows he's not a surgeon.

😕

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