@hjandrew1970 your husbands reaction to the patch is normal for initial use. I experienced the same local skin irritation with initial use too. I recommend using a good skin lotion on the area after removal. I use Cera Ve skin moisturizer and I only use on my upper outer arm’s for the patch now. I had tried using other parts of my body initially but the redness was too irritating. I get a little itching now and then but typically only after lifting weights when I’m stretching my muscles more. Good luck