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What are Short-term ADT's long-term side effects?

Prostate Cancer | Last Active: Oct 19, 2025 | Replies (29)

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Profile picture for brianjarvis @brianjarvis

(I had 28 sessions of proton radiation, with 6 months of Eligard.)

For each guy it’s different, much depending on the planning and preparation decisions made prior to treatments.
Due to the robust resistance-training and cardio program (I’ve always been a gym-rat so, ramping this up was no big deal), my side-effects from ADT were minimal and quite tolerable: just minor “warm” flashes and muscle atrophy. Did have a loss of libido, but no ED. No mood swings, emotions, fatigue, forgetfulness, confusion, memory loss, insomnia, night sweats, weight gain, etc., things that are typically mentioned.
Now (4+ years later), with 20/20 hindsight and T levels all normal, I view that hormone therapy experience as having been just a minor annoyance. All things considered, I got through the hormone therapy quite well.

Good luck with your decision!

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Replies to "(I had 28 sessions of proton radiation, with 6 months of Eligard.) For each guy it’s..."

@brianjarvis ,
Thanks. Nice to hear.

@brianjarvis My experience was substantially the same, except I had 6 months of Orgovyx, but also 28 proton sessions. Very few side effects. Biggest was no libido, not sure about ED since I had no libido, but no ED now 3 months post Orgovyx. My testosterone went from 6 to 110 one month after stopping ADT. I had a few "warm" flashes but that was about the only other SE. I also ran and lifted throughout the treatment, and as with Brian it was something I had been doing regularly before so it wasn't hard to keep it up. All men have different experiences but from the readingI've done, and experiences of men on this forum, exercise seems to the key to reducing SE.