← Return to Experience trying over the counter lithium oronate 5mg daily?

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Profile picture for dalecasto @dalecasto

@randomatomThank you for your response. In my attempt to be brief (due in part to a much longer response disappearing) I posted less than clear information. And perhaps my confusion.

And it is critical that no one give the FDA an excuse to restrict Lithium Orotate.

The whole paragraph states
Dosing
Over-the-counter lithium orotate is promoted as a health supplement for use as a low-dose source of lithium. The recommended daily allowance (RDA) of lithium is 1 mg/day supplemental lithium orotate doses up to 20 mg/day have been suggested.

The fact that the paragraph stated “supplemental lithium orotate doses up to 20 mg/day" followed by "Case reports exist of consumption of higher dosages (up to 240 mg of lithium orotate per day), with no apparent signs of toxicity.
Led me to believe that the dose of 20mg/day indicated “20mg/day [of elemental lithium in the form of lithium orotate] and the higher dosages should be interpreted as up to 240 mg/day of [elemental lithium in the form of] lithium orotate.
Consider also the drugs dot com entry for Lithium carbonate [ /pro/lithobid.html#s-34068-7 ]
Usual Adult Dose for Bipolar Disorder
Extended release formulations: 600 mg orally 2 times a day
Lithium Carbonate is 18.75% elemental lithium, thus the total lithium dosage works out to be 225mg, very close to the 240 grams mentioned in the website
This morning attempted to follow the link to the source cited for the 240 Mg figure. Following the daisy chain of publications I arrived at one that was interesting. It stated that No toxicity or target organs were identified; therefore, a no observed adverse effect level was determined as 400 mg/kg body weight/day. These results are supportive of the lack of a postmarket safety signal from several decades of human consumption. SEE: pubmed.ncbi.nlm.nih dot gov /34146638/
I must be doing something wrong because I keep coming up with a safe dosage of 18 Mg/ per pound.
In any event, keep in mind TRUST NO ONE, especially me (after all, I am also 77 so my mind is probably not as clear as it was). Consider everything as a theory which you need to double check yourself

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Replies to "@randomatomThank you for your response. In my attempt to be brief (due in part to a..."

@dalecasto I too have read all of that and am on 5mg of Lithium
Orotate as a safe dietary supplement. Safe doesn’t mean no one will have a reaction - which is why i found 1mg capsules and worked up to 5mg.

It is a lot to expect most of us to be literate in the difference in elemental levels. I know a lot and what you write i am sure is brilliant - but it gave me a headache

My suggestion is - Stick with a common expression of mg and stay under 5mg - and the consensus is that it will be safe, pending any reaction at an individual level. But we all have the power of judgment and choice.

I notified both my primary care and neurologist of my intention and their response was exactly as you would expect - we don't know enough yet - be patient for human trials. My response was that i so appreciate their input, but my disease course is on a faster track than the research - especially given massive cuts to research budgets. And since no literature i found suggested that low dose or micro dose is dangerous, i am taking this step.

Watch thyroid and eGFR (kidney) levels - both are routine in my annual physical. And drink plenty of water - I shoot for 30-40oz a day- to ensure it doesn't concentrate in your system

Hope that is Helpful.