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← Return to Orgovyx Allergic Reaction
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Prostate Cancer | Last Active: 7 hours ago | Replies (16)
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@brianjarvis Not only does Orgovyx lower T quickly, it also prevents the initial T spike that you get when starting with lupron and abiraterone.
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@nikolai57 Regarding the T spike —>
After starting hormone therapy (like Eligard, Lupron, etc), the body realizes testosterone (T) are slowly dropping, and tells the body to produce more T to offset the slow drop. This may cause a brief “spike” in T which can result in what is called "tumor flare” or “testosterone flare.” - not a good thing to happen since prostate cancer feeds on T.
This temporary flare can be managed by first taking Bicalutimide (Casodex) which blocks T from attaching to prostate cancer cells, which reduces the risk of tumor flare when hormone therapy is started.
Tumor flare does not last long and will go away as the T level goes further down after a hormone injection.
On the other hand, when starting with Relugolix (Orgovyx) or Firmagon, T levels drop so quickly that the body doesn’t have time to realize that T levels are dropping, thus the “testosterone flare” effect doesn’t occur.