I understand that about 40 percent of us are allergic to the binder in Taxol (castor oil), and are thereafter switched to Abraxane, which has the same drug but a more natural binder. I wound up in the emergency room overnight, but I consider that lucky, as the Abraxane infusion only takes an hour total (including flushing, etc), instead of the three I understand Taxol takes. That makes it much easier to ice your hands and feet to avoid neuropathy. I was given benydryl and dexamethasone (a steroid) before each infusion, which left me very comfortable. With a high quality diet and exercise, I had very few side effects from chemo and hope you will have the same experience. Good luck!