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Diagnosed with ILC: Any reconstruction input, implants vs DIEP?
Breast Cancer | Last Active: Oct 18 8:19pm | Replies (16)Comment receiving replies
Thank you for sharing your experiences with ILC. I too was diagnosed with ILC 2 years ago in my right breast, (7mm) oestrogen positive with clear lymph-nodes.
I had radiation with 5 bouts of radiation and have been on Anastrozole.
My biopsy also showed
0-e Cadherin, we much apparently is a significant marker for ILC.
I’m very interested to know if any of your diagnosis also emphasised the loss of e-cadherin.
I’m very interested to know if anyone’s diagnosis has also indicated ‘loss of e-cadherin.’
Thank you,
With kind thoughts
🌻
Replies to "Thank you for sharing your experiences with ILC. I too was diagnosed with ILC 2 years..."
@otas Yes, my diagnosis of ILC indicated loss of e-Cadherin also. I looked it up and it seems to be a hereditary mutation.
@otas thank you for sharing your ILC experience. Like others have commented, I saw neg for e-cadherin on my pathology report and looked it up. In fact, I looked up every term on that report to learn more. That led to finding many of the possible, as well as the rare, gene mutations. So many factors to consider with ILC.
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@otas My pathology report did include the note on E-cadhrin. That is how they determine that it is lobular cancer. "E-cadherin shows loss of membranous staining in the invasive carcinoma, supporting a lobular phenotype."