@heisenberg34 hmm the pain scale ... My daily pain without any pain medication would be a 4-5. When taking Journavx twice a day, and NOT traveling and doing lots of walking - say just a normal week at home - it's a 1-2. When it's time for the next dose, the burning and all-over discomfort starts coming back. I could use it every 8 hours or more often, or a larger dose.