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← Return to Prednisone to Kevzara back to Prednisone. ( Hope not )
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Prednisone to Kevzara back to Prednisone. ( Hope not )
Polymyalgia Rheumatica (PMR) | Last Active: Oct 8 2:17am | Replies (67)Comment receiving replies
@tuckerp I am well aware that it is no approved but a study was done at a major university hospital that had promising results but for some reason was not perused. The study was done by a European company. So that says to me that we don’t all know as much as we think we do
Replies to "@tuckerp I am well aware that it is no approved but a study was done at..."
@grumpa
"I am well aware that it is no approved but a study was done at a major university hospital that had promising results but for some reason was not perused"
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I don't know very much about Crohn's Disease (CD). The following link goes into the details of targeting IL-6 as a treatment option for CD.
The dual role of interleukin-6 in Crohn’s disease pathophysiology:
https://pmc.ncbi.nlm.nih.gov/articles/PMC10722226/
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Too much information for me but I found the following interesting.
"Clinical trials of CD patients have targeted IL-6 signaling in different mechanisms: blocking IL-6, neutralizing IL-6 receptor (IL-6R), or trapping the soluble IL-6/IL-6R complex. These trials have faced challenges and side effects in patients with gastrointestinal perforations and ulcers, for example, all of which highlight the dual role of IL-6 during intestinal inflammation and the need for this cytokine for intestinal tissue integrity."
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I can empathize with people who have multiple autoimmune conditions. My rheumatologist was being honest when he said, "It would be impossible to optimally treat all of my autoimmune conditions."
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@grumpa Boy thats the truth. Dadcue attached an article a few months ago . Whats changed since 1955. Article was discussing PMR but it applies to every auto immune. Cancer. Gerd, Crohns. We might be a little better at treating it but thats about it. We have no idea how to cure something. We have no idea in most cases what causes it. Then the fact that every one of us is different adds more complexity. There are no answers. I dont think any of us know how to respond to someone else. Just share our knowledge . What little we have.