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PSA 11.8 in Jan 25. MRI, biopsy, PSMA test, all lead to positive for prostate cancer with Gleason 4+4. PSA was over 23 when treatment began. Metastasis to left femur top and left shoulder top (both areas significantly injured in a 1997 accident). Began radiation of prostate and left femur in mid Jun for 28 treatments. Waited 2 weeks then received 3 radiation treatments on left shoulder. Received Eligard on July 11 and began Abiraterone on August 18th. August 28th tests showed PSA was undetectable and testosterone was 10. I was fortunate in that side effects were limited to feeling tired and having "heavy" legs from time to time. Abiraterone dosage has been reduced from 1000mg to 250mg and will have PSA checked monthly if it rises then the dosage will return to 1000mg. My oncologist has had patients on the lower dosage as they could not tolerate the side effects. We are doing this because I found a 2018 NIH study on this with a group of only 72 patients. Hope my journey continues to be blessed and wishing all of you the same.
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@glendale
Usually people drop to the 250 mg of Zytiga because they have a low fat breakfast with it. That results in the same amount of medicine reaching the body as taking 1000 mg without eating.
Is that what you did in your case? I know a few people that are doing this.
If you are having fatigue with Zytiga Increasing prednisone from 5 mg to 10 mg can make a big difference. 10 mg is actually one of the standard doses of Prednisone when on Zytiga. Most doctors start with 5 mg however. Some people actually go to 7 1/2 mg as sort of an in between amount.