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← Return to Prednisone to Kevzara back to Prednisone. ( Hope not )
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Prednisone to Kevzara back to Prednisone. ( Hope not )
Polymyalgia Rheumatica (PMR) | Last Active: Oct 8 2:17am | Replies (67)Comment receiving replies
@grumpa not a Dr.s opinion or anything other than an AI search.
"Kevzara (sarilumab) is not an approved treatment for Crohn's disease, and its use is cautioned in patients with active Crohn's. It is an interleukin-6 (IL-6) inhibitor used for conditions like rheumatoid arthritis and polymyalgia rheumatica.
Kevzara and Crohn's disease
Active disease: Due to its immunosuppressive effects, Kevzara should be used with caution in patients with active Crohn's disease.
Immunosuppression and infections: Kevzara increases the risk of serious infections and opportunistic infections. For patients with Crohn's, who may already be taking other immunosuppressants, this risk is a significant concern.
Gastrointestinal perforations: In clinical trials for rheumatoid arthritis, there were reports of gastrointestinal perforations in patients taking Kevzara. This risk is especially relevant for individuals with Crohn's disease, which affects the gastrointestinal tract. "
Replies to "@grumpa not a Dr.s opinion or anything other than an AI search. "Kevzara (sarilumab) is not..."
@tuckerp I am well aware that it is no approved but a study was done at a major university hospital that had promising results but for some reason was not perused. The study was done by a European company. So that says to me that we don’t all know as much as we think we do
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@tuckerp
Thanks Tucker. People have reported bowel perforations which have required them to discontinue Actemra. I was dreading my recent colonoscopy for fear they would find something that would require me to discontinue Actemra.