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← Return to Prednisone to Kevzara back to Prednisone. ( Hope not )
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Prednisone to Kevzara back to Prednisone. ( Hope not )
Polymyalgia Rheumatica (PMR) | Last Active: Oct 8 2:17am | Replies (67)Comment receiving replies
There is nothing on the Kevzara website referencing not to take if a Crohn’s patient. There are many biologics that are approved for Crohn’s. Most come with their own similar warnings like Kevzara and Actamara. Personally I am glad to be back on prednisone I’ve never had the issues with infections while on prednisone. We can be so different with our reactions to medications. I’m highly allergic azathyaprine (Imuran) a dmard, but I was on Methotrexate , a different dmarad a few years.
Replies to "There is nothing on the Kevzara website referencing not to take if a Crohn’s patient. There..."
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@grumpa not a Dr.s opinion or anything other than an AI search.
"Kevzara (sarilumab) is not an approved treatment for Crohn's disease, and its use is cautioned in patients with active Crohn's. It is an interleukin-6 (IL-6) inhibitor used for conditions like rheumatoid arthritis and polymyalgia rheumatica.
Kevzara and Crohn's disease
Active disease: Due to its immunosuppressive effects, Kevzara should be used with caution in patients with active Crohn's disease.
Immunosuppression and infections: Kevzara increases the risk of serious infections and opportunistic infections. For patients with Crohn's, who may already be taking other immunosuppressants, this risk is a significant concern.
Gastrointestinal perforations: In clinical trials for rheumatoid arthritis, there were reports of gastrointestinal perforations in patients taking Kevzara. This risk is especially relevant for individuals with Crohn's disease, which affects the gastrointestinal tract. "