@jade2020 I am truly sorry to hear of these horrible circumstances. I had a pump trial with morphine… no help. Then they used hydromorphone( Dilaudid). That dropped my pain from an 8 to about a 2. My understanding is that this drug is 5x more powerful than morphine. It seems like that should be a better choice in your case. Whatever the case keep fighting for your sister. Keep well and be blessed.