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Pt3b N0 Help

Prostate Cancer | Last Active: 1 day ago | Replies (21)

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Profile picture for jeff Marchi @jeffmarc

@dave27
One thing that is very aggressive was found, Besides seminal vesicle invasion

Non-focal extraprostatic extension" (EPE) describes prostate cancer that has spread beyond the prostate gland into the surrounding tissues in a widespread, extensive manner rather than a limited, pinpoint area. This finding, typically made after a radical prostatectomy (surgery) or potentially seen on imaging like MRI, indicates a more advanced stage of the disease (pT3a) and is a significant risk factor for poorer outcomes and cancer recurrence.

So not only do you have a pT3b but also pT3a

It does say all margins are negative, which is good, but the likelihood of reoccurrence is very high with the two different things that are the shown.

I would definitely want to see a decipher test after this biopsy.

You might discuss this with your doctor and ask what they think about your chance for reoccurrence.

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Replies to "@dave27 One thing that is very aggressive was found, Besides seminal vesicle invasion Non-focal extraprostatic extension"..."

@jeffmarc
Thank you! 🙏
Sure will discuss with doctor in our next appointment. We were told to get PSA and Rectal Profile tests done.

@jeffmarc How can non focal extraprostatic extension and ‘negative margins’ be consistent? They seem almost contradictory in nature.
I had negative margins and a ‘tiny break’ (my urologist’s words) in my capsule and even then I thought it was odd to put the two on the same page.
I wonder what the limit is on how much tissue surrounding the capsule can really be removed in order to get negative margins…?
I get the sense from some posters that they feel ‘positive margins’ is the fault of the surgeon not being diligent; however, I think anatomical considerations (bladder, eg) limit how much a surgeon can excise without causing additional damage.
I think the best policy would be for surgeons to be forthright and say ‘I wasn’t able to get it all’ rather than soft peddling the fact that cancer is still inside your body. JMO,
Phil