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PSA undetectable!

Prostate Cancer | Last Active: Dec 3, 2025 | Replies (29)

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@jc76 - nothing too interesting, I studied psychometrics in graduate school.

I asked about a post-op Decipher @jeffmarc and several times about ultra-sensitive PSA tests @brianjarvis and my surgeon at the Cleveland Clinic doesn't think either are necessary. I'm not too sure what the updated Decipher would add since I'm already considered high risk (no BRCA1/2 mutations). I also asked about a referral to a GU/MO but was told that happens if/when PSA > 0.2.

For now, I'll get my PSA tested every three months. If it becomes detectable, I will up my squeaky wheel level considerably.

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Replies to "@jc76 - nothing too interesting, I studied psychometrics in graduate school. I asked about a post-op..."

@psychometric Same at Mayo. So that's two top-notch that don't do it.

@psychometric
I had RARP in April at Cleveland Clinic and was likewise told that there was no need for a post-op Decipher or an ultra-sensitive PSA. Fortunately both of my PSAs have been "< .02" which I understand to be undetectable.

@psychometric I have 4+5. At Mayo, I think a Decipher is automatic, probably even for a G7. So I had a Decipher and it came in low risk, which was great since 4+5 is high risk.

So if I were you, and of course I'm not, I'd ask for a Decipher. But note: it is a very expensive test. Mine was fully covered by insurance, plus the company that does Decipher offers payment assistance. But you'd want to investigate and then weigh any costs you might incur vs the value of the information.