@jeffmarc you make some great points . You rub on your research - Great job ! Yes, when I got my Salvage radiation my PSA went to 0.010 . Almost nothing . That was about 2.5 years ago . Since then Ive hung around 0.050 - 0,031 . Dr's feel there is healthy cells in the Pelvic bed that was producing some PSA but both the URO and RO said they are not worried about it. I was also discharged from Victoria Cancer clinic ( so I loose contact with my RO there) , BUT he told me to keep in contact with URO . SO I see him every 6 months. Same opinion every time , "your a healthy hiking 62 year old enjoying life ,and have very few normal cell in Prostate bed" . I said how do you know they are not cancerous I asked them both several times. They both say 'we see this all the time, very low levels of PSA going sideways - typically this means normal cells did not get killed on in radiation..." Never been on ADT . Operation 6 years ago , Gleason 3+4 . I actually feel fine .Gene testing done - nothing found . Dad was a prostate guy too and passed away at 67 with it. Late diagnosis I think - although a chemical engineer , he didnt trust Dr's of any sort. Odd for such a brilliant man ! I have No leaks , ED a lot better over time . Here is a site for people on ADT . They are getting great results and help men with their symptoms. https://estradiolinitiative.org . It surrounds the use of Estrediol . Richard a friend of mine is one of the Dr's taking it and has been on ADT for about 22 years . Yep ! 22 years ! Amazing fellow ! Still is very healthy . ADT with estradiol seems to limit Cardio events as well . helps men with 80-90% of symptoms so says people that have taken it under Dr direction . Keep well Jeff .