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Salvage radiation aftermath

Prostate Cancer | Last Active: 10 hours ago | Replies (29)

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Hello @sandguy -
As it was explained to me, the absence of any fluorescence shown by the PET-CT scan meant that the reason I showed chemical recurrence was that only a tiny bit of leftover cancer, not enough to show up, in the bed of the prostate was to blame. I agree, this was puzzling that they’d perform radiation on my pelvic region without proof that anything was there, but evidently my radiation oncologist was right to target the bed of the prostate and remaining lymph nodes because now I’m still knocked back to an undetectable PSA and my testosterone has regained some normalcy.

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Replies to "Hello @sandguy - As it was explained to me, the absence of any fluorescence shown by..."

@makemyday1

I have seen some data in literature that points to the use of SRT to the prostate bed, short term ADT and WPLN radiation in cases where the individual is high risk...

Long ago and far away, when I was experiencing BCR after a "successful" surgery, I recall reading literature from Mayo where the data they collected from BCR pointed to exactly that, more often than not recurrence in high-risk cases extended to the PLNs.

You say "puzzling that they’d perform radiation on my pelvic region without proof that anything was there..." keep in mind I think that even with today's sensitive imaging, there is always the possibility of micro-metastatic disease too small to be detected.

I discussed that idea with my medical team, urologist and radiologist at that point. They said yes, but there was no "long term" data supporting that, I acquiesced to the SOC, SRT to the prostate bed, epic failure, may your outcome be different!

Kevin