@sandguy There is no telling how long it will take for researchers to figure this out. At soon-to-be 77 years old, I doubt I will see definitive answers, let alone actual cures, within my lifetime. In the mean (two meanings of the word) time, one has to just wing it. If I had not had a negative response to the booster, I would be first in line to keep up to date with them. But my experience with the last booster in Oct 2023 set me back dramatically, and I am still not back to where I was before having it. My suspicion - a dark one, I admit - is that COVID will have numerous health outcomes long after first exposure. Just as Hepatitis-C can linger undetected for decades and then flare up with rapid damage to the liver, I suspect COVID may have latent and damaging effects on our bodies.