I think it's an individualized process switching from a PPI to a H2 blocker. I've had 2 fundolication surgeries for severe GERD, but I have not been able to tolerate many PPI's. I tried Pepcid with minimal results, so now I manage with diet & occasional Tums.
I'm a retired RN & I recall when Prilosec came on the market, the PDR showed a 'black box' next to it which signaled severe precautions in taking it. I still think PPI's are NOT meant to be taken long term. I also feel they interfere with complete digestion, plus a whole host of other undesirable side effects. If I need to take them, I do it for a month and stop. I have osteoporosis so I really should avoid them completely. But everyone is different, so it's difficult to make blanket recommendations for everyone to follow. Listen to your body, and your doctor.