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Profile picture for Lisa, Volunteer Mentor @lls8000

@dougmck, I hope you are recovering from the biopsy. There's a lot of waiting through the diagnosis process, which isn't easy, but it can be beneficial.
I can share my own story but remember that it's just one example. My original biopsy was also taken from just a lymph node. There were enough cancerous cells in the lymph node to confirm that it was cancer. The pulmonologist felt there was no need to put me through the risk of going into the lung to get access to the mass. The results from my liquid biopsy did take two weeks to come back. At the time, I wasn't sure that waiting was a good idea. I even questioned if I should have some chemo while we waited. I was symptomatic and getting sicker. Now, I can appreciate the wait because I did have a targetable mutation. Because of that, I was able to avoid chemo and radiation. When I've had a few scares since then, I try to remind myself that unless I'm in the Emergency Department, I have some time to take a breath, review options, get second opinions, and wait (just a bit) for tests.
Do you know if molecular testing/biomarker testing was completed when you were diagnosed in 2008, or with any of your other nodules?

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Replies to "@dougmck, I hope you are recovering from the biopsy. There's a lot of waiting through the..."

@lls8000 Hi. It sounds like you were feeling pretty much the same way I am tonight. The nodule in question was radiated in 2008 and then became malignant again in 2018. We re-radiated it, and did a needle biopsy before doing so. It's now malignant again and spreading. I have questions now as to whether they actually correctly radiated the targeted area or else it's possibly become radiation resistant, which is rare. It turned out that there wasn't sufficient enough tissue to get an accurate molecular reading from the 2018 biopsy, and we tried it again in December when it became malignant again, with the same response from pathology... not enough tissue! We were able to get a PD-L1 reading, however, which was 0. So it's possible that it may have mutated more since December and have a higher PD-L1 reading now, but highly unlikely. I was able to talk my oncologist into ordering a liquid biopsy for tomorrow... the results should be back in a week-10 days. Maybe he'll be willing to to start tx then, because we'll have some sort of confirmation that it's cancer.