Connect
← Return to Newly diagnosed and looking for treatment advice.
Discussion
Newly diagnosed and looking for treatment advice.
Prostate Cancer | Last Active: Oct 11, 2025 | Replies (71)Comment receiving replies
@jc76 Prostox is a new AI test that uses your genetics (swab in mouth test) to determine what your reaction would be to high does SBRT treatment and how it would affect your urinary toxicity. No idea how they can determine this using a swab from your mouth, but mine came back saying I am a bad candidate high does SBRT and that I would have a 95% chance of long term Grade 2 urinary issues. It recommended the longer low dose radiation treatments IMRT which said there was only a 5% chance. This test was ordered by my Mayo Jax Oncologist when he was considering SBRT and it change my path. I am now looking at surgery just to get this out of my body before it is too late.
Replies to "@jc76 Prostox is a new AI test that uses your genetics (swab in mouth test) to..."
@ucfron
Wow! I have mentioned several times that even since I had my treatments reading about new tests and treatments.
I agree with you how that can do that from a mouth swap but that is genetics and A.I, these days. I see you go to Mayo Jacksonville also. Back in 2023 my Mayo Jax R/Os never mentioned that test so must be fairly new.
Did you ever consider going to UFHPTI in Jacksonville? It offers proton radiation versus photon at Mayo Jax. The radiation beam can be controlled not to go pass the prostate or specific area being treated. I was a patient at Mayo Jax like you and met with R/Os several times but Mayo Jax only has photon radiation now until new cancer center is built and on line which will have proton radiation.
There is a lot of discussion about low dose and high does side affects. I think your post reflects about this test confirms the concern some R/Os, urologists and PCPs have about the side affects of high dose versus low dose. My UFHPTI R/O did not like high dose. This was based on what he was seeing with his patients so was real time information. My Mayo PCP said the exact thing of what he was seeing with high dose and low dose. I think getting feedback from doctors treating patients far more real time information is important.
Good luck on your decision. I hope everything is fine with what ever you choose. I wish that test was available when I was diagnosed. I would have liked to have known that information even though my UFHPTI R/O was insistant to doing low dose versus long term based on his personal finding he was seeing with his patients.
Connect
@ucfron
Thanks. Sorry to hear about your test results. But better to know ahead of time than wish you'd gotten the test after experiencing the side effects. I'm still waiting to order my prostox test as both my RO and urologist are on vacation.
Best wishes on your surgery.