Switching from anastrozole to exemestane: Anyone made this switch?

Posted by reginacrick @reginacrick, Jun 1, 2024

My oncologist switched me from Anastrozole to Exemestane.. anybody familiar with this medicine? Side effects? I’m always scared to switch meds.

Interested in more discussions like this? Go to the Breast Cancer Support Group.

Profile picture for lynnpete @lynnpete

@brightlight66 i think i replied in general info. Sorry..new to this😊 also was wondering what you know about "breast defend"? Thanks

Jump to this post

@lynnpete Hi, I had a session with a Naturopathic Doctor who recommended Breast Defend supplement. It's a natural supplement with herbs and DIM. Look it up. DIM can lower overall estrogen levels and reduce the risk of estrogen-related health problems, such as acne, breast cancer, and PMS. So for now, I'm going off AI's and no more meds. Tumor markers just came back normal
Another chiropractor I follow on YouTube recommended "Hormonegenic" supplement which contains DIM and Indole 3 Carbinol (compound found in cruciferous vegetables) to lower estrogen. Also eating broccoli sprouts.
I think my body is too sensitive for these meds and I need to follow a more natural path for now. I'm experimenting and looking for more quality of life!

REPLY
Profile picture for brightlight66 @brightlight66

@lynnpete Hi, I had a session with a Naturopathic Doctor who recommended Breast Defend supplement. It's a natural supplement with herbs and DIM. Look it up. DIM can lower overall estrogen levels and reduce the risk of estrogen-related health problems, such as acne, breast cancer, and PMS. So for now, I'm going off AI's and no more meds. Tumor markers just came back normal
Another chiropractor I follow on YouTube recommended "Hormonegenic" supplement which contains DIM and Indole 3 Carbinol (compound found in cruciferous vegetables) to lower estrogen. Also eating broccoli sprouts.
I think my body is too sensitive for these meds and I need to follow a more natural path for now. I'm experimenting and looking for more quality of life!

Jump to this post

@brightlight66 i totally agree about quality of life. I will check those supplements out. Thanks.hate that there are so many of us out there,but its so helpful to talk/discuss this with peers. sometimes dr.s just can't understand we are dealing with

REPLY
Profile picture for sequoia @sequoia

@celestebradham I was reading your post. Hope you are doing well still. I was interested in how long your did acupuncture. I do acupuncture treatments for scar tissue and nerve damage from my mastectomy. It had relieved my pain and spasms significantly and made such a difference. It’s been a journey, but a positive and bless journey. So thankful for the acupuncture treatment.

Jump to this post

@sequoia
I do acupuncture once a month. It help me keep up my energy levels

REPLY

I switched after about 11 months - my hand joint pain was so extreme I could not do my hobby (sewing). I threatened to quit taking any meds for her to switch me. It took maybe 2 to 3 months - but my hands went from a 7 to about a 1 or 2. So I was really glad to switch. Each drug may affect each person differently. So just try different meds to see what you can tolerate. I made it to my 5 years. The best of luck to you.

REPLY
Profile picture for brightlight66 @brightlight66

@lynnpete Hi, I had stage 2B, surgery, 5 mos chemo (red devil) and 25 radiation treatments, was on Letrozole for 3 months and couldn't take the joint pain, irritability and insomnia. Then a month off and felt wonderful. Just completed a month of Exemestane and the stomach issues and diarrhea were awful and just like you, I only took it 3 times a week. Now thinking of taking "Breast Defend" which is a DIM supplement to support my body.
Not sure what to do next, but I know my oncologist will recommend anastrozole as that's my last choice. I feel SO much better when I don't take any AI's, but the worry is there of a recurrence. What do you think you'll do?

Jump to this post

@brightlight66 My side effects with Letrozole were unbearable. I suffered through for 6 months. I have an RX for Anastrozole, now. I'm going to try it but I don't think I'm going to put up with misery for another 6 months. I have a 10% risk of recurrence even on the meds... I am a young mom. I want to be active with my son.

REPLY
Profile picture for brightlight66 @brightlight66

@lynnpete Hi, I had a session with a Naturopathic Doctor who recommended Breast Defend supplement. It's a natural supplement with herbs and DIM. Look it up. DIM can lower overall estrogen levels and reduce the risk of estrogen-related health problems, such as acne, breast cancer, and PMS. So for now, I'm going off AI's and no more meds. Tumor markers just came back normal
Another chiropractor I follow on YouTube recommended "Hormonegenic" supplement which contains DIM and Indole 3 Carbinol (compound found in cruciferous vegetables) to lower estrogen. Also eating broccoli sprouts.
I think my body is too sensitive for these meds and I need to follow a more natural path for now. I'm experimenting and looking for more quality of life!

Jump to this post

@brightlight66 @lynnpete Can I ask, how old are you ladies? I am 42 trying to navigate the AIs.

REPLY
Profile picture for srussell @srussell

@brightlight66 @lynnpete Can I ask, how old are you ladies? I am 42 trying to navigate the AIs.

Jump to this post

@srussell hi.. im 63. Diagnosis jan of 2024. I felt lump.nothing dhowed on mamogram. Didnt show up until they did MRI. Crazy... Lump was noticeable but mamogram didnt detect.

REPLY
Profile picture for srussell @srussell

@brightlight66 My side effects with Letrozole were unbearable. I suffered through for 6 months. I have an RX for Anastrozole, now. I'm going to try it but I don't think I'm going to put up with misery for another 6 months. I have a 10% risk of recurrence even on the meds... I am a young mom. I want to be active with my son.

Jump to this post

@srussell I completely understand. Please let us all know how it goes. I can guarantee that my oncologist will want to prescribe anastrozole for me too now that I cannot take the side effects from Letrozole and Exemestane. I'm starting to feel SO much better off everything.
I wish you the best and look forward to hearing how it's going. It's taking things one day at a time for all of us here.

REPLY
Profile picture for srussell @srussell

@brightlight66 @lynnpete Can I ask, how old are you ladies? I am 42 trying to navigate the AIs.

Jump to this post

@srussell I'm 66 and was diagnosed in June 2024. I felt the lump, thought it was another fibroid as I've had two but this one was scanned with mammogram, biopsy and bingo. Confirmed with MRI.

REPLY
Profile picture for srussell @srussell

@brightlight66 @lynnpete Can I ask, how old are you ladies? I am 42 trying to navigate the AIs.

Jump to this post

@srussell
I started at 60- so bunches older.

AIs can be tough. But everyone is different. My goal is to hit 5 years on AIs.

REPLY
Please sign in or register to post a reply.