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Newly Diagnosed

Prostate Cancer | Last Active: Oct 31 4:02pm | Replies (32)

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This is what was on my husbands biopsy: prostate, left apex, core needle biopsy adenocarcinoma of prostate, gleason score 8 grade group 4 tumor involves 2 of 2 cores and approximately 15% of sampled tissue. gleasons pattern 4 comprises 100% of the tumor volume. Focal perineural invasion is present

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Replies to "This is what was on my husbands biopsy: prostate, left apex, core needle biopsy adenocarcinoma of..."

@tbyota
A Gleason eight cancer can be treated by surgery or radiation normally. There is one somewhat significant issue.. Focal perineural invasion (PNI) is a significant finding in prostate cancer pathology reports because it indicates an increased risk of cancer spread, progression, and poorer outcomes, including higher rates of biochemical recurrence and potential metastasis.

The thing is, it is not widespread PNI Which is a much worse condition it is just in a spot.

I had PNI in my biopsy and I’m still alive 15 years later, even though I have a serious genetic problem. I know a lot of other people that had PNI but it was not a significant factor in their overall survival either.

I would think your husband could be treated and would have a long term Progression free survival.

It sure would make sense to get a decipher test to see if there is A high chance of recurrence.