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DiscussionSwitching from anastrozole to exemestane: Anyone made this switch?
Breast Cancer | Last Active: Oct 5, 2025 | Replies (63)Comment receiving replies
Replies to "Hi. I stopped because of the headaches. I only took every other day. And then o..."
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@lynnpete Hi, I had stage 2B, surgery, 5 mos chemo (red devil) and 25 radiation treatments, was on Letrozole for 3 months and couldn't take the joint pain, irritability and insomnia. Then a month off and felt wonderful. Just completed a month of Exemestane and the stomach issues and diarrhea were awful and just like you, I only took it 3 times a week. Now thinking of taking "Breast Defend" which is a DIM supplement to support my body.
Not sure what to do next, but I know my oncologist will recommend anastrozole as that's my last choice. I feel SO much better when I don't take any AI's, but the worry is there of a recurrence. What do you think you'll do?