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I wanna stop taking methotrexate and prednisone.

Polymyalgia Rheumatica (PMR) | Last Active: 5 days ago | Replies (16)
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Profile picture for claudette2024 @claudette2024

@dadcue
Thank you.
My rheumatologist is leaving the decision up to me.
Methotrexate or Kevzara or Rincoq. She did not mention Actemra. After a year of pred I need to get off. My body looks like a war zone.

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Replies to "@dadcue Thank you. My rheumatologist is leaving the decision up to me. Methotrexate or Kevzara or..."
Mike | @dadcue | 6 days ago

I wish you luck with whatever you decide.

Rinvoq is the latest modern treatment for GCA that was FDA approved very recently in April 2025. If Actemra stops working for me I would likely be switched to Rinvoq. It is also FDA approved for some of the other autoimmune disorders that I have.

You must have a good rheumatologist. She is aware of the latest treatment options that are available. Rinvog works differently compared to both Actemra and Kevzara. It comes in pill form so no injections or infusions.

Any of these medications might work better than methotrexate. Sometimes insurance companies require that methotrexate be tried first before approving the more expensive biologics.

I think good rheumatologists want their patients off Prednisone as soon as possible. These alternatives to prednisone for PMR/GCA are seen as steps in the right direction.

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