@tisme After experiencing horrific withdrawal symptoms two months after tapering Effexor, I went online to look for help. The most helpful information for me (aside from this site) was the information presented by Mark Horowitz via YouTube and in his book, The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs (by Horowitz & David Taylor). I purchased an extra copy for my doctor, and one for my pharmacist. (They both thanked me, saying they found it helpful for other patients as well.) My pharmacist created the liquid solution based on information in the book. His assistant created a spreadsheet allowing for a 10% reduction over time. I'm down to 25mg per day (also available in an immediate release tablet), and plan to proceed with a 5% reduction so as to increase my chances of successfully weaning from this drug. I reduce the dose when I feel ready, whether that's weeks or months. Good luck with your efforts.