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Has anyone had Signatera testing (genetics-based cancer test)?

Gynecologic Cancers | Last Active: Oct 1 6:06pm | Replies (41)
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Profile picture for ginmav @ginmav

I am new to this site. Last year was diagnosed with stage 3 ovarian cancer and peritoneal cancer. Had 6 months of chemo and radical hysterectomy. CA125 is now under 4 and taking Lynparza.

I have a question what is this
Signature test? I will have to discuss with my Dr.

I am so happy to find this site.
Also anybody else taking lynparza.

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Replies to "I am new to this site. Last year was diagnosed with stage 3 ovarian cancer and..."
jandrew1922 | @jandrew1922 | Sep 28 6:02pm

@ginmav
I am on Lynparza 400mg daily.

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val64 | @val64 | Sep 28 6:18pm

The Signatera test (by the company Natera) is intended to detect cancer recurrences by looking for low levels of DNA derived from your cancer in your blood. So it serves the same purpose as testing for CA125. How well it works is a subject of debate. There are definitely false negatives. If it's positive, that means there are cells derived from your cancer somewhere in your body. But apparently sometimes the source is hard to find, and a tumor may not grow. So these are considered false positives.

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