There is no taper that is required in order to discontinue Kevzara. The dose of the injections are the same so the dose isn't gradually decreased. Sometimes the interval between injections is increased before stopping Kevzara but the dose stays the same.

I'm doing Actemra infusions. My infusion dose can be adjusted higher or lower but it has never been lowered with the intent of tapering me off Actemra. I currently do the lowest recommended monthly infusion dose of Actemra. There isn't any plan to stop my monthly infusions.

My monthly infusion was abruptly stopped once when supplies of Actemra were limited during Covid. I didn't have a sudden relapse but my symptoms gradually returned after a few months. I wouldn't call it a sudden flare or a relapse. It was more like PMR was still active when treatment with Actemra was stopped so treatment needed to be continued. In the absence of Actemra, I had to take Prednisone again. When Actemra was restarted, I was able to taper off Prednisone again rapidly in a matter of a few weeks rather than years.

I don't know how a person is supposed to differentiate between symptoms of Prednisone withdrawal and symptoms of PMR. The main reason Prednisone is tapered is because of adrenal suppression. Abruptly stopping Prednisone could result in an adrenal crisis. As scary as that sounds it is relatively rare. People usually have symptoms of Prednisone withdrawal before an adrenal crisis occurs.

Overall ... I think I'm fortunate to be able to be treated with Actema indefinitely. I don't have side effects and Actemra works much better that Prednisone ever did. Since I am currently off of Prednisone, my adrenal function has been restored which makes my life much better.