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Profile picture for dave56pa @dave56pa

@val64 Thank you for the info. My oncologist was on vacation last visit so I asked the PA for a copy of the report: I’m learning as I just diagnosed in late July. mNSCLC in the lung, liver, clavicle, hips, pelvis, spine. Biopsies tissue & liquid then Radiation now Chemo.
Anyway the biomarkers are
KRAS G12V 21%
TP53 V157F 22%
TP53 R213Q 1%
ARID1A G1460Wfs31 20%
ARID1A P1583Lfs29 .1%
CCNE1 amplification Med++
“patient is free of biomarkers associated with FDA approved therapies”
So I should probably have a genetic counselor explain what all those nbrs mean in terms of my kids? As I’m well aware of what they mean to me.

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Replies to "@val64 Thank you for the info. My oncologist was on vacation last visit so I asked..."

No, you don't need to worry about your kids based on that report. Those percentages show that those mutations are all somatic, only in the cancer. Any mutation that you could pass down would be detected at at least 50%.