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Thank you for the responses.
2023 Pathology: Tumor: Type: Acinar adenocarcinoma. Grade: Grade Group 4 (GS 4+4=8)
Intraductal Carcinoma (IDC): Present. IDC Incorporated into Grade: Yes.
Cribriform Glands: Present.
Greatest Dimension of Dominant Nodule: 17mm.
Seminal Vesicle Invasion: Present, right.
Lymph vascular Invasion: not identified.
Margins: All margins negative for invasive carcinoma.
All regional lymph nodes (7 examined) negative for tumor.
Pathologic Stage Class: (pTNM, AJCC 8th Edition); Primary Tumor (pT): pT3b; pN Category: pN0
Prostate specimen...Left seminal vesicle was measured, the right is absent and may have been transected at the base of the prostate. [Interesting]

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Replies to "Thank you for the responses. 2023 Pathology: Tumor: Type: Acinar adenocarcinoma. Grade: Grade Group 4 (GS..."

@stjosephstmary
You have multiple very aggressive things going on with your prostate cancer. All three of the following things mean that your cancer is much more aggressive than your Gleason score shows.

Intraductal Carcinoma (IDC): Present. IDC Incorporated into Grade: Yes.
Cribriform Glands: Present.
Seminal Vesicle Invasion: Present, right.

If you just had one of these three things, it would not be good but you have all three and getting salvage radiation as soon as possible makes a lot of sense.

You should do some searching about these three items, you will find that they are very aggressive. They actually have said a UCF seminar that if you have cribriform and intraductal That really puts a five in your Gleason score.

You should ask if the cribriform Is small or large. Large cribriform Is much more aggressive.

I’m not surprised they want to do salvage radiation as soon as possible, Your chance of reoccurrence is very high. With all three of these things, a decipher scores is probably not even worth doing, It would tell you your chance of reoccurrence, but you have so many aggressive things going on that the chance of reoccurrence is very high.

Be proactive about your treatment, Your progression free survival is dependent on getting the right treatment as soon as possible and staying on good treatment.

According to most medical advisors with all these negative things you have you should be on ADT plus an ARSI (Zytiga or a lutamide). Speak to an oncologist about this, Preferably not a medical oncologist you need to speak to a Genito urinary oncologist, They are the ones that specialize in prostate cancer. If you could mention where you live in the country, we could give you information on oncologist to speak to.

Be aware that if you have reoccurrence before three years, you are much more likely to have future reoccurrences. I’ve had four but I’m still alive after 15 years because I’ve stayed on the correct drug treatments for my situation.