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Replies to "Funny this popped up today, saw my primary care doctor yesterday and asked about adding collagen..."
@jozer According to Harvard Health, a review and analysis of 19 studies, published in the International Journal of Dermatology, that had a total of 1,125 participants. Those who used collagen supplements saw an improvement in the firmness, suppleness, and moisture content of the skin, with wrinkles appearing less noticeable. That sounds promising, but it's unclear if these skin improvements were actually due to collagen. Most of the trials used commercially available supplements that contained more than collagen: vitamins, minerals, antioxidants, coenzyme Q10, hyaluronic acid, and chondroitin sulfate were among the additional ingredients.
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@jozer I tried collagen well-researched supplements for an entire year, and saw no difference in skin, hair or nails. I do not have osteoporosis or even osteopenia, but have a strong family history of it, so I hoped it might help there too. My DEXA at the end of that year showed no change from 2 years prior, so probably no help there either.
As your primary told you, these supplements are unregulated, so we can only hope they contain what is promised (and nothing more). After a year of no particular benefit, I decided it was a failed experiment and quit.