Radiation vs. Prostectomy (nerve sparing)

Posted by Setters and Birds @jonathanack, Sep 22 12:11pm

Hellos all,
I am curious if other patients on this site have a similar situation to mine and what their course of treatment (decision of treatment plan) was for them?

My oncologist (a surgeon with over 4k minimally invasive procedures) has advised that either surgery or radiation (SBRT - 5 weeks) with 30 days of ADT will both be equally effective. Radiologists (Sloan alum/Weil-Cornell - 36 years old) advises the same. I appreciate any advice or insight you can share.
Thank you all & I wish all of you health and good luck in your journey.
Jon

I am leaning toward radiation re: faster recovery.
I am advised the side effects will be nearly the same for someone with my diagnosis, age, lifestyle, etc.

PSA: 3.74
Cribriform (2 tumors = 3+4)
Decipher: .72
Age: 63 (1 uncle with gleason 6 active surveilance - parents lived well into the 80's with no cancer)
No other meaningful health issues.
No meaningful symptoms.

The diagnosis:
4 tumors:
1. Acinar Adenocarcinoma
Grade Group and Gleason Score: Grade group 2 (Gleason Score 3 + 4 = 7)
Architectural Patterns of Gleason Pattern 4: Cribriform Glands, Poorly Formed
Glands
Percentage of Pattern 4/5: 20%

2. Acinar Adenocarcinoma
Grade Group and Gleason Score: Grade group 2 (Gleason Score 3 + 4 = 7)
Architectural Patterns of Gleason Pattern 4: Cribriform Glands, Fused Glands,
Poorly Formed Glands
Estimated Percentage of Prostatic Tissue Involved by Tumor: 27%
Perineural Invasion: Present

3.Acinar Adenocarcinoma
Grade Group and Gleason Score: Grade group 1 (Gleason Score 3 + 3 = 6)

4. Acinar Adenocarcinoma
Grade Group and Gleason Score: Grade group 1 (Gleason Score 3 + 3 = 6)

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Profile picture for rbtsch1951 @rbtsch1951

I am in the midst of SBRT (5 treatment regimen) and ADT (Lupron) for Stage IIIC, Grade 5 PCa. I am approaching my 74th birthday and have enjoyed an active sex-life until now. I worry more about the loss of libido and ED from treatment than I do about the possibility of a recurrence. Still, I am happy to know that good treatments exist and hope that I can continue to live a happy and fulfilling lifetime. I hope to successfully not allow the sexual repercussions of the treatment define my happiness and sense of well being. Time, I am sure, will tell …

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@rbtsch1951 If you’ve enjoyed a healthy sex life up to age 74 you are one lucky guy!
Mine ended at age 64 and others on the forum were cut short much earlier than that.
Speaking for myself, I LOVED my sex life but after a time you do move on…I love my wife and feel worse for her since she is an innocent bystander in all this.
You do come to understand (thanks to surgery, radiation and ADT) that there IS more to life, you just couldn’t appreciate it with your erect penis blocking the view!

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Profile picture for bcarey @bcarey

In spring of 2024 I was diagnosed with prostate cancer I was considered "high risk" my decipher was 0.96 most recent PSA 12.74. Gleason score 4+4. I met with two sets of doctors from two different hospitals. I come from a Wall St background. I did realize that this was a business. The goal was to get patients, lay out their options 1) do nothing 2) have the surgery to remove the entire prostate 3) radiation treatment. I chose surgery which took place in Aug of 2024. At the conclusion of surgery the surgeon believed the cancer was confined to the interior of the prostate. The lab results proved differently there was a compromised area where the cancer cells had escaped the prostate. Within 6-8 weeks my PSA confirmed this situation. A PET scam was done which showed cancer cells in my abdomen area. I then began 6 months of homone therapy along with 2 months of radiation treatment. I have done it all. I must say at this point my PSA is .05 The consequences of the surgery and the nerve damage is that I am left castrated. The emotions and depression with this situation ( I am 67 yrs old) are brutal. The doctors where never candid about the consequences of the surgery. As you come off the homone treatment and your testosterone levels which mine were measured at a low of 15. (normal for a 60 year old male is 750-1000). My testosterone at 15 was that of a 8-10 year old boy. As the hormone treatment ended in April of 2025 and the testostrone levels slowly creep up your libido returns. At this point you realize you are incapable of having an intimate monment with you wife or partner. It is as if the surgery took my soul and manhood. It is important that you have an experienced and talented surgeon inorder to avoid perment nerve damage. These nerves which surround the prostate connect with your brain, when sexually excited send blood flow to you penis creating an erection. I have used pumps and needles in the past few months with limited success. I must say the doctors want to make you cancer free and extend your life. Your quality of life and conserquences of treatment are a secondary concern. Fighting caner is a business. I am a paying customer of the hospital where I chose to have the surgery and treatment. There is no turning back the clock. The decisions I have made I must live and die with, going forward.

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@bcarey Sorry they did you like that. The surgeon I saw convinced me not to do it by describing what could happen, (no sex, wearing a diaper), so I opted for radiation. I got the opposite from that guy who told me nothing about side effects and the receptionist handed me a 3 page handout as I was leaving. My side effects left me with being able to have sex but urination frequency/burning and bowel movements 3 times a day sucks. I hope it's worth it and I do survive longer because of it and there are no more side effects coming. The ones I have have gotten worse not better since I finished my treatment 7 + months ago. Anyway, good luck.

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