Hi Lioness, No I have not. I took Methotrexate for about two years, it helped a lot for me, only it made my hair start thinning. I stopped taking this, because I thought I was smarter than my doctor. The only thing that helped my itchy scalp was two or three drops of tea tree oil (really strong smell) in Any shampoo. Needless to say I went back to the doctors and she put me on Leflunomide (generic) I just started this. I have drug insurance. Take my advice Costco has cheap prices, cheaper than Walmart! Sandra