@jlharsh hello and thank you! I'm. A little confused so maybe you can help clarify. So you're saying the group of doctors didn't know where the heart attacks started but think they start where the blockages of hard calcium are the biggest? And then you mentioned an initial thought and what you believe to be the biggest "danger zone, " which seem to be where the smaller blockages are. May I ask what that based on? I hear what you're saying about wanting to solidify the mushy plaque and reduce inflammation. That makes sense to me. I'm taking a statin and changed my diet drastically since the calcium score, and moving around/walking more. I think that's all I can do right now. My angio was denied by the insurance company so the doctors are working on resubmitting and hoping it gets through this time. I think I think my words were I feel like I didn't have any life force - not that I wanted to improve my quality of life - although, I think they go hand in hand. What I meant by that is I don't have a lot of energy (sometimes can barely function) and now that I know I have a very high calcium score it feels as though a blockage might be the culprit in not getting the life force that I need through my body - ie blood flow. Thanks again for reaching out. I'm basically just scared and like many of the others here feel like a walking time bomb. It's surreal and hard not to think about.