My cousin is a DES daughter. She had stage 4 endometrial cancer at age 50. She nearly hemorrhaged to death because doctors insisted her heavy non-stop bleeding was premenopausal. She had a complete hysterectomy and they found nodes in her stomach cavity that were affected. She went through chemo. She had to end it a little early due to complications. But she has had no reoccurrences and its been over 10 years. The fatigue took years to recover from. But she is doing very well.