I don't know that there is any evidence that Reclast is safer than Evenity for one's knees or much of anything else. Maybe heart issues? If you thoroughly check out Reclast you will find that some people have severe life altering issues that do not go away. What's unknown is what percentage of those taking Reclast or Evenity have significant long lasting problems due to taking them. Myself I'm much more afraid of Reclast than Evenity. Of course I've already done a year of Evenity with great success and no side effects worth mentioning. After Evenity you still have to take something to hold onto the gains you get from Evenity. And many then take Reclast. If one follows that route they will have likely gained significant bone from Evenity and be much further ahead in the game than if they had just started with Reclast.