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Recovery time after Anastrozole/aromatase inhibitors

Breast Cancer | Last Active: 4 hours ago | Replies (70)

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Profile picture for megunique @megunique

This has been so helpful to read chats and experiences. I was diagnosed at 69 and did 5 years on anastrazole. I am 1 month off the medication. I asked a lot of questions over those 5 years and learned a lot if this helps anyone. Yes symptoms can occur at any point and that is why my oncologist would ask at every appointment if any new side effects appeared. It is because this medication has somewhat of a cumulative effect. The longer you block estrogen the more it can impact you. I had initial muscles cramps but they went away. I think largely because I pushed myself to exercise and strength training. I had joint stiffness but thought it was from lifting weights. Now that I am off anastrazole for 1 month the stiffness is reduced. But I am far from full recovery. My most serious side effect was lack of sleep no matter what sleep aids I tried. I am slowly sleeping better but still have a lot of fatigue. I have a higher creatinine on the drug and while I maintained my weight ok for 4.5 years the last 5 months I gained weight despite a good diet, exercise and barely eating candy. The metabolic impact is frustrating and makes no sense to me.
I am told now that it can take 3-9 months for your body to recover. So I am trying to be grateful research and these meds have improved survival rates so significantly and that i am alive. I think in general not enough information is given about how women recover from hormone blocker. I could have prepared better mentally.

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Replies to "This has been so helpful to read chats and experiences. I was diagnosed at 69 and..."

@megunique
I was on it for the 5 years, and have now been off a little over 2 months.. some of the milder side effects have improved, but my joint and muscle pain has not.. I don’t even see an improvement yet. I was getting a little discouraged until I saw your post. If you’ve heard it can take 3-9 months, I still have some hope that it will get better.. as of now, I haven’t even seen an improvement..

@megunique
Your diagnosis (stage 1A, IDC) is the same as mine; and I'm 68. You also did well in exercising and making a purposeful plan for sleep. I do those things now (and have always been fit). I still await surgery, etc but really do not want to take any of the AI's; but might consider tamoxifen low-dose.
I do not take any medications currently; have low blood pressure and never did HRT. To think of being on a medication for 5 years is daunting to me!
Do you think it was worth it for you? Thank you for sharing all that you have experienced!