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DiscussionHow long to does one stay on hormone therapy Orgovyx?
Prostate Cancer | Last Active: Sep 25 3:44pm | Replies (27)Comment receiving replies
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The thing is, they discussed the fact that this is true with intermediate patients. So those with extensive PC do not benefit apparently.
As demonstrated below, intermediate risk patients who were biomarker negative did not benefit from short-term ADT. Conversely, those with a positive biomarker status had significantly decreased distant metastases rates when short-term ADT was added to radiotherapy (HR: 0.33, p< 0.001):
Here is an article from ASCO that actually discusses this
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html