Your 3+4 Gleason Looks pretty good. The issue is that UCSF had a seminar where they discussed cribriform. They said it made a 3+4 have a five in it. And that sort of syncs up with your decipher score of .72 which is pretty high and bodes for a reoccurrence at some point. They also said that SBRT radiation isn’t effective with cribriform.

I had a 3+4 at 62. I decided on surgery because my father had radiation and died from prostate cancer. After surgery, they said my Gleason was a 4+3 . My PSA started rising after 3 1/2 years and I had to have salvage radiation. It started rising 2 1/2 years after that and I had to go on Lupron. I’m still around 15 years after that surgery, The drugs they have today work quite well. I have A genetic problem BRCA2, So that’s why it keeps coming back. There was no decipher score when I had surgery 15 years ago.

While you have cribriform in more than one place It doesn’t really say whether it is large cribriform. That is much more aggressive and maybe is why your decipher is so high. You could ask them whether it is large or not.

Surgery is much more effective if you have cribriform, because if you have a reoccurrence (Which your decipher says is likely), you can have salvage radiation. If you have radiation to start with, you can’t do that. If you have surgery, you want to make sure you talk to the doctor about sparing the nerves, That can allow you to get an erection after surgery without using drugs that have to be injected.

Getting an hereditary, genetic test is a good idea. If you have certain genetic issues, there are new drugs to treat them. You can get one free here
http://Prostatecancerpromise.org
They will send you a spit tube and in about three weeks a genetic counselor will call you to discuss the results. Don’t check the box to have your doctor involved. In that case they won’t send anything until they speak to your doctor.