i have had piriformus syndrome for 30 years. Tight butt muscles pressing on the nerves interwined with the muscles. Exercise helps and NOT SITTING to for long! Also, when things used to send me through the roof a shot of Torodol in my butt resolved everything until the next time. I no longer have that kind of flare. I walk and stretch regularly and see a MFR therapist 2x a month. I am 68. Used to both me HORRIBLY at 40. There is hope!