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How does one distinguish between PN and lymphadema? Although my legs don't appear to be swollen, I have this sensation of a lot of fluid built up in my calves. My skin feels tight, and when I swim (40 laps non-stop, 3 x week) I have the sensation that I'm wearing heavy boots on my feet. I'm a good swimmer, so it is not technique. I've taken to wearing OneCompress socks on my legs at night, which helps minimally. I also have regular (light) compression socks that provide some relief when things feel really bad. I've tried magnesium cream on my legs, which seems to do little for me. I have very painful leg cramps at night sometimes, which wakes me up. I've mentioned all this to my rheumatologist, but he hasn't offered any thoughts.

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Replies to "How does one distinguish between PN and lymphadema? Although my legs don't appear to be swollen,..."

I had a lymphoscintigram done at Mayo Clinic which was when I was diagnosed with lymphedema in my legs - https://www.mayoclinic.org/diseases-conditions/lymphedema/diagnosis-treatment/drc-20374687. In addition to wearing the compression socks during the day, I use a moisturizing cream on the legs just because that's near where the peripheral nerves are and dry skin doesn't help. At night I elevate my feet a few inches which helps the swelling go down more during the night. I used to add a couple of folded blankets under the mattress but I ended up getting an adjustable bed which makes it a lot easier. Not sure if you've tried the search function but there are quite a few member discussions on leg cramps at night that might be helpful - https://connect.mayoclinic.org/search/?search=leg+cramps+at+night.