For those of us with BE, nebulizing and airway clearance (e.g. huff coughs) will help keep the airways clear. The goal is to reduce exasperations and the subsequent infections. There are only a few studies out there on nebulizing for MAC treatment, but the few I have read have shown a potential link with nebulizing and spontaneous conversion. I was diagnosed with MABC in November 2024, and my Pulmonologist ordered the compressor and wrote script for the saline, the same day he gave me the diagnosis. By May 2025 my MABC cultures were negative. There is a study starting in Portland with 100 participants looking at using nebulization with 7% saline as a treatment for MAC. My hunch is that they will see an increase in spontaneous conversion. As for sputum cultures, I was sending in monthly sputum samples to NJH and I was not on antibiotics. NJH labs do NTM colony counts and that helps determine the disease progression or improvement. There was a post a few days ago on this site that listed 31 or 33 BE NTM Clinics, maybe you can find one close to you. The fact that you were diagnosed with MAC 2 years ago and nebulizing was not brought up, is a red flag. I had a local Pulm and ID doctor but I chose to go to NJH and I am so glad I did. There are really great videos and studies posted on this site=in just the past week. Also if you have time, you can find the 2025 BE NTM Patient and Family Conference on You tube. It's about 7 hours of lectures but you can see the individual lecturers (to the right of the screen). Kathy