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Methotrexate risks versus inflammation risks
Autoimmune Diseases | Last Active: Sep 29 11:13am | Replies (11)Comment receiving replies
Good afternoon,
I have EGPA and have been on Prenizone, Cyclophosphamide,Gabapentine , and two other drugs for bone and infection risk. I have reached remission after four months of treatment and have moved to Methotrexate 20 mg a week starting yesterday. I compare the risk of my previous regime to the Methotrexate and am willing to accept the risk since a loss of remission would be devastating. It seems that balance is always the better of two evils associated with these challenging autoimmune diseases. I can understand your frustration and pray that you find answers.
Replies to "Good afternoon, I have EGPA and have been on Prenizone, Cyclophosphamide,Gabapentine , and two other drugs..."
Have any of you explored the EGPA biologic drug Nucala to control your symptoms? I have been on it for 18 months and am doing well, off prednisone, and very grateful. At close to 80 years old. I have very little side effects and , so far, reduced immunity has not been a problem.
God bless your journeys.
MTH13
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Thankfully, I don't have your history. I had only the mildest joint problems that always go after 48 hours, it's called palindromic. In took hydroxychloroquine for 12 weeks until side effects started in my eyes but I've not taken any other drugs.
I've looked up as far as I can go about risks. My risk of a heart attack or a stroke is 2 or 3 times. But 2 or 3 times tiny is still tiny. There's no history of either in my family, I'm fit, tall and slim, exercise 5-6 days a week and eat a low UPF diet with plenty of fruit and veg.
I'm hoping to goodness that my next test shows my CRP dropping again.
I hope methotrexate works for you, it's a very effective drug if you need to take it.