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Discussion44yr PSA180 Gleason9 non-metastatic. Surgery or Treatment?
Prostate Cancer | Last Active: Sep 27 11:03am | Replies (112)Comment receiving replies
Replies to "I am new and completely ignorant. What is BCR?"
Hi Chief901,
Welcome to MCC! As there are many acronyms used in communication about prostate cancer (PCa), I found the following thread very helpful!
https://connect.mayoclinic.org/discussion/prostate-cancer-related-abbreviations-what-acronym-would-you-add/
This community has been a huge help to me in getting oriented to all of the many facets of prostate cancer. I hope you will continue to post your questions and comments as participation is what makes this forum so valuable to others.
Bill
Biochemical Recurrence (BCR) in Prostate Cancer
BCR refers to the detection of elevated prostate-specific antigen (PSA) levels after treatment for prostate cancer, indicating a possible recurrence of the disease.
Definition and Incidence:
BCR is typically defined as two consecutive PSA values ≥0.2 ng/mL after radical prostatectomy (RP) or ≥2 ng/mL after radiation therapy (RT).
The incidence of BCR varies depending on factors such as age, Gleason score, and treatment modality.
After RP, the 5-year BCR rate is around 20-40%, while after RT it is around 10-30%.
Risk Factors:
Higher Gleason score, Positive lymph nodes, Younger age, Higher PSA levels at diagnosis, and Rapid PSA rise after treatment.