← Return to Starting BIG 3 tonight ….

Discussion
lynncat avatar

Starting BIG 3 tonight ….

MAC & Bronchiectasis | Last Active: 4 days ago | Replies (34)

Comment receiving replies
Profile picture for terrimn @terrimn

Hi there! On the daily same Big 3 doses as you, plus twice daily inhaled Amikacin. I wanted to let you know what my BE/MAC/MAI pharmacist from Mayo Clinic advised to get the most effective absorption of meds: NEVER take Rifampin with Azithromycin bc the Rifampin decreases Azithromycin absorption by over 50%!!! Macrolides are the #1 fighter against MAC, so you want to absorb the full dose. Also, INHALED Amikacin goes directly to the lungs, versus IV Amikacin, thereby decreasing chances of cruddy systemic side
effects.
I'm certainly not saying that your ID doc doesn't know what's best for you, but my Mayo ID doc and his pharmacist are adamant about making sure that all meds prescribed are most efficiently and maximally absorbed. It's why the pharmacist personally calls MAC patients to explain the schedule. I've updated my daily schedule if you're interested how I do it all without feeling like it's taking over my life. We are all different bodies with different physiological characteristics. Best wishes for testing negative sooner than later!

Jump to this post


Replies to "Hi there! On the daily same Big 3 doses as you, plus twice daily inhaled Amikacin...."

thank you for your answer. does that mean that you take the Rifampin at a different time of the day ? do you mind sharing your medicine schedule ? I was only told to do at night with dinner , however last night was 9.30 so I forced myself to eat something to take the pills. I am planning to do 8 ish? after supper? I have dinner ready for kids 6 pm ,, so too early ? How are you feeling ?